[
  {
    "Question": "Which gland is primarily responsible for regulating metabolism through hormone secretion?",
    "Answer": "B",
    "Explanation": "The thyroid gland produces hormones like thyroxine that regulate the body's metabolic rate.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/8/8a/Thyroid_gland_anatomy.svg/1200px-Thyroid_gland_anatomy.svg.png",
    "OptionA": "Pituitary gland",
    "OptionB": "Thyroid gland",
    "OptionC": "Adrenal gland",
    "OptionD": "Pancreas",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Hormone Regulation",
    "Item": 1,
    "Type": "multiple choice",
    "Path": "Endocrine system/hormone regulation"
  },
  {
    "Question": "Which hormone is secreted by the pancreas to lower blood glucose levels?",
    "Answer": "C",
    "Explanation": "Insulin is secreted by the beta cells of the pancreas and helps lower blood sugar by facilitating cellular glucose uptake.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Pancreas_diagram.svg/1200px-Pancreas_diagram.svg.png",
    "OptionA": "Glucagon",
    "OptionB": "Adrenaline",
    "OptionC": "Insulin",
    "OptionD": "Cortisol",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Hormone Regulation",
    "Item": 2,
    "Type": "multiple choice",
    "Path": "Endocrine system/hormone regulation"
  },
  {
    "Question": "Which of the following is NOT an endocrine gland?",
    "Answer": "D",
    "Explanation": "The spleen is part of the lymphatic system and is not an endocrine gland.",
    "PictureURL": "",
    "OptionA": "Pituitary gland",
    "OptionB": "Thyroid gland",
    "OptionC": "Adrenal gland",
    "OptionD": "Spleen",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Endocrine Glands",
    "Item": 3,
    "Type": "multiple choice",
    "Path": "Endocrine system/endocrine glands"
  },
  {
    "Question": "What hormone does the adrenal medulla primarily secrete in response to stress?",
    "Answer": "A",
    "Explanation": "The adrenal medulla secretes adrenaline (epinephrine), which prepares the body for 'fight or flight' responses.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/7/7b/Adrenal_gland_anatomy.svg/1200px-Adrenal_gland_anatomy.svg.png",
    "OptionA": "Adrenaline",
    "OptionB": "Cortisol",
    "OptionC": "Aldosterone",
    "OptionD": "Insulin",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Endocrine Glands",
    "Item": 4,
    "Type": "multiple choice",
    "Path": "Endocrine system/endocrine glands"
  },
  {
    "Question": "Which type of diabetes is characterized by the body's inability to produce insulin?",
    "Answer": "B",
    "Explanation": "Type 1 diabetes is an autoimmune condition where the pancreas produces little or no insulin.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Diabetes_illustration.svg/1200px-Diabetes_illustration.svg.png",
    "OptionA": "Type 2 diabetes",
    "OptionB": "Type 1 diabetes",
    "OptionC": "Gestational diabetes",
    "OptionD": "Prediabetes",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Diabetes",
    "Item": 5,
    "Type": "multiple choice",
    "Path": "Endocrine system/diabetes"
  },
  {
    "Question": "Which hormone increases blood glucose levels by stimulating glycogen breakdown in the liver?",
    "Answer": "D",
    "Explanation": "Glucagon, secreted by alpha cells of the pancreas, raises blood sugar by promoting glycogen breakdown.",
    "PictureURL": "",
    "OptionA": "Insulin",
    "OptionB": "Adrenaline",
    "OptionC": "Thyroxine",
    "OptionD": "Glucagon",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Hormone Regulation",
    "Item": 6,
    "Type": "multiple choice",
    "Path": "Endocrine system/hormone regulation"
  },
  {
    "Question": "What condition results from an underactive thyroid gland producing insufficient thyroid hormone?",
    "Answer": "C",
    "Explanation": "Hypothyroidism is caused by low thyroid hormone levels, leading to symptoms like fatigue and weight gain.",
    "PictureURL": "",
    "OptionA": "Hyperthyroidism",
    "OptionB": "Diabetes mellitus",
    "OptionC": "Hypothyroidism",
    "OptionD": "Cushing's syndrome",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Thyroid Disorders",
    "Item": 7,
    "Type": "multiple choice",
    "Path": "Endocrine system/thyroid disorders"
  },
  {
    "Question": "Which hormone is released by the pituitary gland to stimulate the thyroid gland?",
    "Answer": "A",
    "Explanation": "Thyroid-stimulating hormone (TSH) is secreted by the pituitary to regulate thyroid hormone production.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Pituitary_gland_diagram.svg/1200px-Pituitary_gland_diagram.svg.png",
    "OptionA": "Thyroid-stimulating hormone (TSH)",
    "OptionB": "Adrenocorticotropic hormone (ACTH)",
    "OptionC": "Growth hormone (GH)",
    "OptionD": "Oxytocin",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Hormone Regulation",
    "Item": 8,
    "Type": "multiple choice",
    "Path": "Endocrine system/hormone regulation"
  },
  {
    "Question": "Which of the following is a common symptom of hyperthyroidism?",
    "Answer": "B",
    "Explanation": "Weight loss despite increased appetite is a typical symptom of hyperthyroidism due to increased metabolism.",
    "PictureURL": "",
    "OptionA": "Weight gain",
    "OptionB": "Weight loss",
    "OptionC": "Cold intolerance",
    "OptionD": "Constipation",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Thyroid Disorders",
    "Item": 9,
    "Type": "multiple choice",
    "Path": "Endocrine system/thyroid disorders"
  },
  {
    "Question": "Which hormone regulates calcium levels in the blood by increasing calcium absorption from bones?",
    "Answer": "D",
    "Explanation": "Parathyroid hormone (PTH) increases blood calcium by stimulating bone resorption and calcium absorption.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Parathyroid_glands_diagram.svg/1200px-Parathyroid_glands_diagram.svg.png",
    "OptionA": "Calcitonin",
    "OptionB": "Insulin",
    "OptionC": "Thyroxine",
    "OptionD": "Parathyroid hormone (PTH)",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Endocrine Glands",
    "Item": 10,
    "Type": "multiple choice",
    "Path": "Endocrine system/endocrine glands"
  },
  {
    "Question": "Which type of diabetes is most commonly associated with insulin resistance rather than insulin deficiency?",
    "Answer": "A",
    "Explanation": "Type 2 diabetes is characterized by the body's ineffective use of insulin, known as insulin resistance.",
    "PictureURL": "",
    "OptionA": "Type 2 diabetes",
    "OptionB": "Type 1 diabetes",
    "OptionC": "Gestational diabetes",
    "OptionD": "Diabetes insipidus",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Diabetes",
    "Item": 11,
    "Type": "multiple choice",
    "Path": "Endocrine system/diabetes"
  },
  {
    "Question": "Which hormone is responsible for the 'fight or flight' response and increases heart rate and blood pressure?",
    "Answer": "B",
    "Explanation": "Adrenaline (epinephrine) is released by the adrenal medulla and triggers physiological changes for rapid response.",
    "PictureURL": "",
    "OptionA": "Cortisol",
    "OptionB": "Adrenaline",
    "OptionC": "Insulin",
    "OptionD": "Thyroxine",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Hormone Regulation",
    "Item": 12,
    "Type": "multiple choice",
    "Path": "Endocrine system/hormone regulation"
  },
  {
    "Question": "Which gland is often called the 'master gland' because it controls other endocrine glands?",
    "Answer": "C",
    "Explanation": "The pituitary gland regulates many other endocrine glands by releasing various stimulating hormones.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Pituitary_gland_diagram.svg/1200px-Pituitary_gland_diagram.svg.png",
    "OptionA": "Thyroid gland",
    "OptionB": "Adrenal gland",
    "OptionC": "Pituitary gland",
    "OptionD": "Pancreas",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Endocrine Glands",
    "Item": 13,
    "Type": "multiple choice",
    "Path": "Endocrine system/endocrine glands"
  },
  {
    "Question": "What is the primary effect of cortisol released by the adrenal cortex?",
    "Answer": "D",
    "Explanation": "Cortisol helps regulate metabolism, reduces inflammation, and assists the body in responding to stress.",
    "PictureURL": "",
    "OptionA": "Increase insulin secretion",
    "OptionB": "Stimulate thyroid hormone production",
    "OptionC": "Lower blood glucose levels",
    "OptionD": "Increase blood glucose and suppress immune response",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Hormone Regulation",
    "Item": 14,
    "Type": "multiple choice",
    "Path": "Endocrine system/hormone regulation"
  },
  {
    "Question": "Which thyroid disorder is characterized by an enlarged thyroid gland, often due to iodine deficiency?",
    "Answer": "A",
    "Explanation": "A goiter is an enlargement of the thyroid gland, commonly caused by iodine deficiency affecting hormone production.",
    "PictureURL": "https://upload.wikimedia.org/wikipedia/commons/thumb/6/6a/Goiter_illustration.svg/1200px-Goiter_illustration.svg.png",
    "OptionA": "Goiter",
    "OptionB": "Hypothyroidism",
    "OptionC": "Hyperthyroidism",
    "OptionD": "Thyroid cancer",
    "OptionE": "",
    "OptionF": "",
    "OptionG": "",
    "TestName": "Endocrine System Practice Test",
    "Content Type": "multiple choice",
    "Title": "Endocrine System – Thyroid Disorders",
    "Item": 15,
    "Type": "multiple choice",
    "Path": "Endocrine system/thyroid disorders"
  }
]